Mitochondria-Mediated Programmed Cell Death in <i>Saccharomyces cerevisiae</i> Induced by Betulinic Acid Is Accelerated by the Deletion of <i>PEP4</i> Gene
In this work, using <em>Saccharomyces cerevisiae</em> as a model, we showed that BetA could inhibit<br />cell proliferation and lead to lethal cytotoxicity accompanying programmed cell death (PCD).<br />Interestingly, it was found that vacuolar protease Pep4p played a pivotal...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-11-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/7/11/538 |