Integrated analysis of transcriptomic and metabolomic profiling reveal the p53 associated pathways underlying the response to ionizing radiation in HBE cells
Abstract Background Radiation damage to normal tissues is a serious concern. P53 is a well-known transcription factor which is closely associated with radiation-induced cell damage. Increasing evidence has indicated that regulation of metabolism by p53 represents a reviving mechanism vital to protec...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Cell & Bioscience |
Online Access: | http://link.springer.com/article/10.1186/s13578-020-00417-z |