Integrated analysis of transcriptomic and metabolomic profiling reveal the p53 associated pathways underlying the response to ionizing radiation in HBE cells

Abstract Background Radiation damage to normal tissues is a serious concern. P53 is a well-known transcription factor which is closely associated with radiation-induced cell damage. Increasing evidence has indicated that regulation of metabolism by p53 represents a reviving mechanism vital to protec...

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Bibliographic Details
Main Authors: Ruixue Huang, Xiaodan Liu, He Li, Yao Zhou, Ping-Kun Zhou
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Cell & Bioscience
Online Access:http://link.springer.com/article/10.1186/s13578-020-00417-z