Subcellular Localization and Dynamics of the Bcl-2 Family of Proteins

Bcl-2 family proteins are recognized as major regulators of the mitochondrial pathway of apoptosis. They control the mitochondrial outer membrane permeabilization (MOMP) by directly localizing to this organelle. Further investigations demonstrated that Bcl-2 related proteins are also found in other...

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Bibliographic Details
Main Authors: Nikolay Popgeorgiev, Lea Jabbour, Germain Gillet
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2018.00013/full