A meta-analysis of the relationship between RARβ gene promoter methylation and non-small cell lung cancer.

BACKGROUND: Hypermethylation of CpG islands in tumor suppressor gene plays an important role in carcinogenesis. Many studies have demonstrated that hypermethylation in promoter region of RARβ gene could be found with high prevalence in tumor tissue and autologous controls such as corresponding non-t...

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Bibliographic Details
Main Authors: Feng Hua, Nianzhen Fang, Xuebing Li, Siwei Zhu, Weisan Zhang, Jundong Gu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4010458?pdf=render