Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in <it>Vitro</it> and in <it>Vivo</it>

Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in <it>Vitro</it> and in <it>Vivo</it>

<p>Abstract</p> <p>Background</p> <p>Cyclooxygenase-2(COX-2) promotes carcinogenesis, tumor proliferation, angiogenesis, prevention of apoptosis, and immunosuppression. Meanwhile, COX-2 over-expression has been associated with tumor behavior and prognosis in several can...

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Bibliographic Details
Main Authors: Dai Zhi-Jun, Ma Xiao-Bin, Kang Hua-Feng, Gao Jie, Min Wei-Li, Guan Hai-Tao, Diao Yan, Lu Wang-Feng, Wang Xi-Jing
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Cancer Cell International
Subjects:
Breast cancer
Cyclooxygenase-2
Anti-tumor
DMBA
Online Access:http://www.cancerci.com/content/12/1/53

Internet

http://www.cancerci.com/content/12/1/53

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