VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor

VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor

The potential role of the very low density lipoprotein (VLDL) receptor in mediating VLDL-induced plasminogen activator inhibitor-1 (PAI-1) expression was studied in vitro. Cultured endothelial cells incubated with VLDL showed an increased secretion of PAI-1. This response to VLDL could be completely...

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Bibliographic Details
Main Authors: Lennart Nilsson, Mats Gåfvels, Leena Musakka, Katharina Ensler, Dudley K. Strickland, Bo Angelin, Anders Hamsten, Per Eriksson
Format: Article
Language:English
Published: Elsevier 1999-05-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
transfection
VLDL response element
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032126X

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http://www.sciencedirect.com/science/article/pii/S002222752032126X

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