Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

How emotions affect memory is an open question. Here the authors establish learnt hopeful and learnt helpless mouse models, and find that posterior basolateral amygdala to ventral hippocampal CA1 monosynaptic glutamatergic inputs link emotions to spatial memory performance.

Bibliographic Details
Main Authors: Ying Yang, Zhi-Hao Wang, Sen Jin, Di Gao, Nan Liu, Shan-Ping Chen, Sinan Zhang, Qing Liu, Enjie Liu, Xin Wang, Xiao Liang, Pengfei Wei, Xiaoguang Li, Yin Li, Chenyu Yue, Hong-lian Li, Ya-Li Wang, Qun Wang, Dan Ke, Qingguo Xie, Fuqiang Xu, Liping Wang, Jian-Zhi Wang
Format: Article
Language:English
Published: Nature Publishing Group 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11935

Internet

https://doi.org/10.1038/ncomms11935

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