The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity.

The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity.

The Scc2-Scc4 complex is essential for loading the cohesin complex onto DNA. Cohesin has important roles in chromosome segregation, DSB repair, and chromosome condensation. Here we report that Scc2 is important for gene expression in budding yeast. Scc2 and the transcriptional regulator Paf1 collabo...

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Bibliographic Details
Main Authors: Musinu Zakari, Rhonda Trimble Ross, Allison Peak, Marco Blanchette, Chris Seidel, Jennifer L Gerton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4503661?pdf=render

Internet

http://europepmc.org/articles/PMC4503661?pdf=render

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