Effect of antipsychotics on breast tumors by analysis of the Japanese Adverse Drug Event Report database and cell-based experiments

Effect of antipsychotics on breast tumors by analysis of the Japanese Adverse Drug Event Report database and cell-based experiments

Abstract Background Since antipsychotics induce hyperprolactinemia via the dopamine D2 receptor, long-term administration may be a risk factor for developing breast tumors, including breast cancer. On the other hand, some antipsychotic drugs have been reported to suppress the growth of breast cancer...

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Bibliographic Details
Main Authors: Tae Maeshima, Ryosuke Iijima, Machiko Watanabe, Satoru Yui, Fumio Itagaki
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Breast tumor
Antipsychotics
JADER
MCF-7
Blonanserin
Online Access:https://doi.org/10.1186/s40780-021-00199-7

Internet

https://doi.org/10.1186/s40780-021-00199-7

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