Effect of antipsychotics on breast tumors by analysis of the Japanese Adverse Drug Event Report database and cell-based experiments
Abstract Background Since antipsychotics induce hyperprolactinemia via the dopamine D2 receptor, long-term administration may be a risk factor for developing breast tumors, including breast cancer. On the other hand, some antipsychotic drugs have been reported to suppress the growth of breast cancer...
Main Authors: | Tae Maeshima, Ryosuke Iijima, Machiko Watanabe, Satoru Yui, Fumio Itagaki |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | Journal of Pharmaceutical Health Care and Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40780-021-00199-7 |
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