The Transcriptome of Human Endometrial Mesenchymal Stem Cells Under TGFβR Inhibition Reveals Improved Potential for Cell-Based Therapies

The Transcriptome of Human Endometrial Mesenchymal Stem Cells Under TGFβR Inhibition Reveals Improved Potential for Cell-Based Therapies

Mesenchymal stem/stromal cells (MSCs) are multipotent cells with favorable properties for cell therapies and regenerative medicine. Human endometrium harbors a small population of perivascular, clonogenic MSCs (eMSCs) identified by the SUSD2 marker. As for other MSCs, eMSCs require extensive in vitr...

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Bibliographic Details
Main Authors: Shanti Gurung, Sarah Williams, James A. Deane, Jerome A. Werkmeister, Caroline E. Gargett
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human endometrial MSC
RNA-sequencing
TGF-βR
culture expansion
angiogenesis
anti-fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00164/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2018.00164/full

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