PARP inhibitors in female reproductive system cancers
PARP-1 and PARP-2 enzymes are one of six known DNA damage repair systems - nitrogenous base excision repair. PARP inhibitor disrupts excision repair and under the conditions of the absence of another pathway of DNA damage repair (homologous recombination) can cause apoptosis in tumor cells. One of t...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Habib O.N.
2017-06-01
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| Series: | Современная онкология |
| Subjects: | |
| Online Access: | https://modernonco.orscience.ru/1815-1434/article/viewFile/27128/pdf |