IgG glycosylation in autoimmune diseases
Immunoglobulin G (IgG) is the most abundant glycoprotein in human serum. All IgG subclasses have a single-conserved N-linked glycosylation site at Asn297 of the heavy chain and 10–30% of IgGs are N-glycosylated also in a Fab region. N-glycans of Fc are sialylated and fucosylated biantennary complex-...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Index Copernicus International S.A.
2018-11-01
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Series: | Postępy Higieny i Medycyny Doświadczalnej |
Subjects: | |
Online Access: | http://phmd.pl/gicid/01.3001.0012.7351 |