Imbalance of Circulating Th17 and Regulatory T Cells in Alzheimer’s Disease: A Case Control Study

The neuropathological hallmarks of Alzheimer’s disease (AD), i.e., neuritic plaques and neurofibrillary tangles, consist of beta amyloid peptides (Aβ) and hyperphosphorylated Tau. These are accompanied by reactive microglia and astrocytes in the vicinity of the neuritic plaques and by changes to the...

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Bibliographic Details
Main Authors: Timo Jan Oberstein, Lava Taha, Philipp Spitzer, Janina Hellstern, Martin Herrmann, Johannes Kornhuber, Juan Manuel Maler
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
Th1
Tau
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01213/full