Efficiently cleaved HIV-1 envelopes: can they be important for vaccine immunogen development?

The enormous diversity of HIV-1 is a significant impediment in selecting envelopes (Envs) that can be suitable for designing vaccine immunogens. While tremendous progress has been made in developing soluble, trimeric, native-like Env proteins, those that have elicited neutralizing antibodies (Abs) i...

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Bibliographic Details
Main Authors: Supratik Das, Rajesh Kumar, Shubbir Ahmed, Hilal Ahmad Parray, Sweety Samal
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Therapeutic Advances in Vaccines and Immunotherapy
Online Access:https://doi.org/10.1177/2515135520957763