CYK4 relaxes the bias in the off-axis motion by MKLP1 kinesin-6

Analysing the 3D movement of MKLP1 motors, Maruyama et al. find that dimeric C. elegans MKLP1 drives a left-handed helical motion around the microtubule with minimum protofilament switching to the right side whereas less persistent motions are driven by monomers or by heterotetramers with CYK4. Thes...

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Bibliographic Details
Main Authors: Yohei Maruyama, Mitsuhiro Sugawa, Shin Yamaguchi, Tim Davies, Toshihisa Osaki, Takuya Kobayashi, Masahiko Yamagishi, Shoji Takeuchi, Masanori Mishima, Junichiro Yajima
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01704-2