Mapping differentiation under mixed culture conditions reveals a tunable continuum of T cell fates.
Cell differentiation is typically directed by external signals that drive opposing regulatory pathways. Studying differentiation under polarizing conditions, with only one input signal provided, is limited in its ability to resolve the logic of interactions between opposing pathways. Dissection of t...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-07-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC3728017?pdf=render |