Osteosarcoma microenvironment: whole-slide imaging and optimized antigen detection overcome major limitations in immunohistochemical quantification.

Osteosarcoma microenvironment: whole-slide imaging and optimized antigen detection overcome major limitations in immunohistochemical quantification.

BACKGROUND: In osteosarcoma survival rates could not be improved over the last 30 years. Novel biomarkers are warranted to allow risk stratification of patients for more individual treatment following initial diagnosis. Although previous studies of the tumor microenvironment have identified promisin...

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Bibliographic Details
Main Authors: Pierre Kunz, Jörg Fellenberg, Linda Moskovszky, Zoltan Sápi, Tibor Krenacs, Johannes Poeschl, Burkhard Lehner, Miklos Szendrõi, Volker Ewerbeck, Ralf Kinscherf, Benedikt Fritzsching
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940945?pdf=render

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http://europepmc.org/articles/PMC3940945?pdf=render

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