Where Do AQP4 Antibodies Fit in the Pathogenesis of NMO?

Recent advances in the field of neuromyelitis optica (NMO) research provided convincing evidence that anti-AQP4 antibody (AQP4-Ab) not only serves as a highly specific disease marker, but also plays an essential role in the pathogenesis of the disease. Although it is now widely recognized that AQP4-...

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Bibliographic Details
Main Authors: Makoto Kinoshita, Yuji Nakatsuji
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Multiple Sclerosis International
Online Access:http://dx.doi.org/10.1155/2012/862169