Mathematical modeling of heterogeneous electrophysiological responses in human β-cells.

Electrical activity plays a pivotal role in glucose-stimulated insulin secretion from pancreatic β-cells. Recent findings have shown that the electrophysiological characteristics of human β-cells differ from their rodent counterparts. We show that the electrophysiological responses in human β-cells...

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Bibliographic Details
Main Authors: Michela Riz, Matthias Braun, Morten Gram Pedersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3879095?pdf=render