Immune Dysregulation Mimicking Systemic Lupus Erythematosus in a Patient With Lysinuric Protein Intolerance: Case Report and Review of the Literature

Immune Dysregulation Mimicking Systemic Lupus Erythematosus in a Patient With Lysinuric Protein Intolerance: Case Report and Review of the Literature

Lysinuric protein intolerance (LPI) is an inborn error of metabolism caused by defective transport of cationic amino acids in epithelial cells of intestines, kidneys and other tissues as well as non-epithelial cells including macrophages. LPI is caused by biallelic, pathogenic variants in SLC7A7. Th...

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Bibliographic Details
Main Authors: Josefina Longeri Contreras, Mabel A. Ladino, Katherine Aránguiz, Gonzalo P. Mendez, Zeynep Coban-Akdemir, Bo Yuan, Richard A. Gibbs, Lindsay C. Burrage, James R. Lupski, Ivan K. Chinn, Tiphanie P. Vogel, Jordan S. Orange, M. Cecilia Poli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pediatrics
Subjects:
lysinuric protein intolerance
systemic lupus erythematosus
hemophagocytic lymphohistiocytosis
immune mediated glomerulonephritis
case report
systemic lupus–erythematosus
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.673957/full

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https://www.frontiersin.org/articles/10.3389/fped.2021.673957/full

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