Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release

Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release

This study aimed to prepare poly (D, L-lactic-co-glycolic acid) microspheres (PLGA-Ms) by a modified solid-in-oil-in-water (S/O/W) multi-emulsion technique in order to achieve sustained release with reduced initial burst and maintain efficient drug concentration for a prolonged period of time. Compo...

Full description

Bibliographic Details
Main Authors: Ni Dong, Chune Zhu, Junhuang Jiang, Di Huang, Xing Li, Guilan Quan, Yang Liu, Wen Tan, Xin Pan, Chuanbin Wu
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Microspheres
PLGA
Peptides
Lipid nanoparticles
Sustained drug release
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618304392

Internet

http://www.sciencedirect.com/science/article/pii/S1818087618304392

Similar Items