Aspirin Inhibits IKK-β-mediated Prostate Cancer Cell Invasion by Targeting Matrix Metalloproteinase-9 and Urokinase-Type Plasminogen Activator

Aspirin Inhibits IKK-β-mediated Prostate Cancer Cell Invasion by Targeting Matrix Metalloproteinase-9 and Urokinase-Type Plasminogen Activator

Background/Aims: Aspirin has been demonstrated to possess potent chemopreventive and anticancer effects on prostate cancer. However, the more detailed molecular mechanisms of aspirin to suppress prostate cancer cell invasion have not been clearly elucidated. Methods: Transwell assays were performed...

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Bibliographic Details
Main Authors: Chongjun Shi, Nini Zhang, Yang Feng, Jiewei Cao, Xuyi Chen, Bin Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Invasion
Matrix metalloproteinase
Nuclear factor-kappa B
Prostate cancer
Urokinase-type plasminogen activator
Online Access:http://www.karger.com/Article/FullText/464434

Internet

http://www.karger.com/Article/FullText/464434

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