Gene suppression approaches to neurodegeneration

Abstract Gene suppression approaches have emerged over the last 20 years as a novel therapeutic approach for the treatment of neurodegenerative diseases. These include RNA interference and anti-sense oligonucleotides, both of which act at the post-transcriptional level, and genome-editing techniques...

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Bibliographic Details
Main Authors: Rhia Ghosh, Sarah J. Tabrizi
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13195-017-0307-1