A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12

A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12

Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither chemotherapeutic nor targeted therapeutic approaches h...

Full description

Bibliographic Details
Main Authors: Alexa Burger, Aleksandr Vasilyev, Ritu Tomar, Martin K. Selig, G. Petur Nielsen, Randall T. Peterson, Iain A. Drummond, Daniel A. Haber
Format: Article
Language:English
Published: The Company of Biologists 2014-07-01
Series:Disease Models & Mechanisms
Subjects:
HRASV12
Cancer
Chordoma
Drug treatment
Rapamycin
Zebrafish
Online Access:http://dmm.biologists.org/content/7/7/907

Internet

http://dmm.biologists.org/content/7/7/907

Similar Items