Canine parvovirus VP2 protein expressed in silkworm pupae self-assembles into virus-like particles with high immunogenicity.

Canine parvovirus VP2 protein expressed in silkworm pupae self-assembles into virus-like particles with high immunogenicity.

The VP2 structural protein of parvovirus can produce virus-like particles (VLPs) by a self-assembly process in vitro, making VLPs attractive vaccine candidates. In this study, the VP2 protein of canine parvovirus (CPV) was expressed using a baculovirus expression system and assembled into parvovirus...

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Bibliographic Details
Main Authors: Hao Feng, Gui-qiu Hu, Hua-lei Wang, Meng Liang, Hongru Liang, He Guo, Pingsen Zhao, Yu-jiao Yang, Xue-xing Zheng, Zhi-fang Zhang, Yong-kun Zhao, Yu-wei Gao, Song-tao Yang, Xian-zhu Xia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3894932?pdf=render

Internet

http://europepmc.org/articles/PMC3894932?pdf=render

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