CD27−CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression

CD27−CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression

Summary: Although peripheral B cell dysfunction in early HIV infection is established, how B cell subsets are altered by HIV infection is poorly understood. While investigating B cell subsets among individuals recently infected with HIV, we observe an accumulation of CD27−CD38+ B cells and find that...

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Bibliographic Details
Main Authors: Yajing Fu, Zining Zhang, Zhijun Yang, Yongjun Jiang, Xiaoxu Han, Junjie Xu, Zhenxing Chu, Haibo Ding, Sijia He, Hong Shang
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
early HIV infection
B cell subset
HIV disease progression
transitional B cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721007208

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http://www.sciencedirect.com/science/article/pii/S2211124721007208

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