CD27−CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression
Summary: Although peripheral B cell dysfunction in early HIV infection is established, how B cell subsets are altered by HIV infection is poorly understood. While investigating B cell subsets among individuals recently infected with HIV, we observe an accumulation of CD27−CD38+ B cells and find that...
Main Authors: | Yajing Fu, Zining Zhang, Zhijun Yang, Yongjun Jiang, Xiaoxu Han, Junjie Xu, Zhenxing Chu, Haibo Ding, Sijia He, Hong Shang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-07-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124721007208 |
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