A Murine Hypertrophic Cardiomyopathy Model: The DBA/2J Strain.

A Murine Hypertrophic Cardiomyopathy Model: The DBA/2J Strain.

Familial hypertrophic cardiomyopathy (HCM) is attributed to mutations in genes that encode for the sarcomere proteins, especially Mybpc3 and Myh7. Genotype-phenotype correlation studies show significant variability in HCM phenotypes among affected individuals with identical causal mutations. Morphol...

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Bibliographic Details
Main Authors: Wenyuan Zhao, Tieqiang Zhao, Yuanjian Chen, Fengbo Zhao, Qingqing Gu, Robert W Williams, Syamal K Bhattacharya, Lu Lu, Yao Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4524617?pdf=render

Internet

http://europepmc.org/articles/PMC4524617?pdf=render

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