Prognostic Stratification of GBMs Using Combinatorial Assessment of IDH1 Mutation, MGMT Promoter Methylation, and TERT Mutation Status: Experience from a Tertiary Care Center in India

Prognostic Stratification of GBMs Using Combinatorial Assessment of IDH1 Mutation, MGMT Promoter Methylation, and TERT Mutation Status: Experience from a Tertiary Care Center in India

This study aims to establish the best and simplified panel of molecular markers for prognostic stratification of glioblastomas (GBMs). One hundred fourteen cases of GBMs were studied for IDH1, TP53, and TERT mutation by Sanger sequencing; EGFR and PDGFRA amplification by fluorescence in situ hybridi...

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Bibliographic Details
Main Authors: Suvendu Purkait, Supriya Mallick, Vikas Sharma, Anupam Kumar, Pankaj Pathak, Prerana Jha, Ahitagni Biswas, Pramod Kumar Julka, Deepak Gupta, Ashish Suri, Ashish Datt Upadhyay, Vaishali Suri, Mehar C Sharma, Chitra Sarkar
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316300353

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http://www.sciencedirect.com/science/article/pii/S1936523316300353

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