SMAD6, positively regulated by the DNM3OS-miR-134-5p axis, confers promoting effects to cell proliferation, migration and EMT process in retinoblastoma

Abstract Background Retinoblastoma (RB) is acknowledged to be the commonest intraocular malignancy in infants and children and the outcome of RB patients is unfavorable due to limited early diagnosis and effective therapy. SMAD family member 6 (SMAD6) has been reported in the initiation and progress...

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Bibliographic Details
Main Authors: Hui Wang, Xiang Ji
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-020-1103-8