Post-exposure administration of chimeric antibody protects mice against European, Siberian, and Far-Eastern subtypes of tick-borne encephalitis virus.

Post-exposure administration of chimeric antibody protects mice against European, Siberian, and Far-Eastern subtypes of tick-borne encephalitis virus.

Tick-borne encephalitis virus (TBEV) is the most important tick-transmitted pathogen. It belongs to the Flaviviridae family and causes severe human neuroinfections. In this study, protective efficacy of the chimeric antibody chFVN145 was examined in mice infected with strains belonging to the Far-Ea...

Full description

Bibliographic Details
Main Authors: Andrey L Matveev, Irina V Kozlova, Oleg V Stronin, Yana A Khlusevich, Elena K Doroshchenko, Ivan K Baykov, Oksana V Lisak, Ljudmila A Emelyanova, Olga V Suntsova, Vera A Matveeva, Julia S Savinova, Nina V Tikunova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215075

Internet

https://doi.org/10.1371/journal.pone.0215075

Similar Items