Network connectivity determines cortical thinning in early Parkinson’s disease progression

In Parkinson’s disease (PD), neurodegeneration spreads from the brainstem to the cerebral cortex. Here, in a longitudinal study of PD patients, the authors found that cortical thinning followed neural connectivity from a “disease reservoir”.

Bibliographic Details
Main Authors: Y. Yau, Y. Zeighami, T. E. Baker, K. Larcher, U. Vainik, M. Dadar, V. S. Fonov, P. Hagmann, A. Griffa, B. Mišić, D. L. Collins, A. Dagher
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02416-0