Drug resistance of cancer cells is crucially affected by expression levels of ABC-transporters

Dasatinib (DAS), a second generation of tyrosine kinase inhibitor (TKI), represents excellent choice for the treatment of chronic myeloid leukemia resistant to imatinib. Unfortunately, recent laboratory studies suggested that antiproliferative effect of DAS might be significantly reduced due to t...

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Bibliographic Details
Main Authors: Petr Mlejnek, Petr Dolezel, Eliska Ruzickova
Format: Article
Language:English
Published: Pensoft Publishers 2017-02-01
Series:BioDiscovery
Subjects:
Online Access:https://biodiscovery.pensoft.net/article/11211/download/pdf/