Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort.

Tuberculosis incidence in resource poor countries remains high. We hypothesized that immune modulating co-infections such as helminths, malaria, and HIV increase susceptibility to latent tuberculosis infection (LTBI), thereby contributing to maintaining the tuberculosis epidemic.Adults with sputum-p...

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Bibliographic Details
Main Authors: Irene A Biraro, Moses Egesa, Frederic Toulza, Jonathan Levin, Stephen Cose, Moses Joloba, Steven Smith, Hazel M Dockrell, Achilles Katamba, Alison M Elliott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4221037?pdf=render