Methyl 3,4-Dihydroxybenzoate Enhances Resistance to Oxidative Stressors and Lifespan in C. elegans Partially via daf-2/daf-16

Methyl 3,4-Dihydroxybenzoate Enhances Resistance to Oxidative Stressors and Lifespan in C. elegans Partially via daf-2/daf-16

Genetic studies have elucidated mechanisms that regulate aging; however, there has been little progress in identifying drugs that retard ageing. Caenorhabditis elegans is among the classical model organisms in ageing research. Methyl 3,4-dihydroxybenzoate (MDHB) can prolong the life-span of C. elega...

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Bibliographic Details
Main Authors: Xiang-Nan Mi, Li-Fang Wang, Yang Hu, Jun-Ping Pan, Yi-Rong Xin, Jia-Hui Wang, Hai-Ju Geng, Song-Hui Hu, Qin Gao, Huan-Min Luo
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Molecular Sciences
Subjects:
Methyl 3,4-dihydroxybenzoate
ageing
Caenorhabditis elegans
daf-2
daf-16/FoxO
oxidative stress
Online Access:http://www.mdpi.com/1422-0067/19/6/1670

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http://www.mdpi.com/1422-0067/19/6/1670

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