A Tissue-Engineered Tracheobronchial In Vitro Co-Culture Model for Determining Epithelial Toxicological and Inflammatory Responses

A Tissue-Engineered Tracheobronchial In Vitro Co-Culture Model for Determining Epithelial Toxicological and Inflammatory Responses

Translation of novel inhalable therapies for respiratory diseases is hampered due to the lack of in vitro cell models that reflect the complexity of native tissue, resulting in many novel drugs and formulations failing to progress beyond preclinical assessments. The development of physiologically-re...

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Bibliographic Details
Main Authors: Luis Soriano, Tehreem Khalid, Fergal J. O’Brien, Cian O’Leary, Sally-Ann Cryan
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
respiratory tissue engineering
collagen
toxicology
3D in vitro models
co-culture
epithelium
Online Access:https://www.mdpi.com/2227-9059/9/6/631

Internet

https://www.mdpi.com/2227-9059/9/6/631

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