Dimyristoylphosphotidylcholine induces conformational changes in apoB that lowers lipoprotein(a)

Lipoprotein(a) [Lp(a)] is assembled by the binding of apolipoprotein B (apoB) lysine residues on LDL to lysine binding sites in apolipoprotein(a) [apo(a)] and the subsequent formation of a disulphide bond between apoB and apo(a). In this study, we induced changes in apoB conformation by adding phosp...

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Bibliographic Details
Main Authors: Yan-Ting Wang, Anne von Zychlinski, Sally P.A. McCormick
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520308361