Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production

Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production

In vitro studies have shown that the binding site for microsomal triglyceride transfer protein (MTP) is within the first 17% of apoB (apoB-17). Expression of apoB-48 in McArdle cells decreases endogenous lipoprotein production; however, overexpression of human apoB in transgenic mice does not decrea...

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Bibliographic Details
Main Authors: Zhaohui Li, Yuko Kako, Ling Pang, Mason W. Freeman, Jane M. Glick, Xinzhong Wang, Ira J. Goldberg
Format: Article
Language:English
Published: Elsevier 2000-12-01
Series:Journal of Lipid Research
Subjects:
adenovirus
microsomal triglyceride transfer protein
lipoprotein lipase
very low density lipoproteins
chylomicrons
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032352X

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http://www.sciencedirect.com/science/article/pii/S002222752032352X

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