Cell-autonomous role of GFRα1 in the development of olfactory bulb GABAergic interneurons

GFRα1, a receptor for glial cell line-derived neurotrophic factor (GDNF), is critical for the development of the main olfactory system. The olfactory bulb (OB) of Gfra1 knockout mice shows significant reductions in the number of olfactory sensory neurons, mitral and tufted cells, as well as all majo...

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Bibliographic Details
Main Authors: Sabrina Zechel, Diana Fernandez-Suarez, Carlos F. Ibáñez
Format: Article
Language:English
Published: The Company of Biologists 2018-05-01
Series:Biology Open
Subjects:
RMS
SVZ
Online Access:http://bio.biologists.org/content/7/5/bio033753