Elevated Soluble Urokinase Plasminogen Activator Receptor and Proenkephalin Serum Levels Predict the Development of Acute Kidney Injury after Cardiac Surgery

Elevated Soluble Urokinase Plasminogen Activator Receptor and Proenkephalin Serum Levels Predict the Development of Acute Kidney Injury after Cardiac Surgery

Acute kidney injury (AKI) develops in up to 40% of patients after cardiac surgery. The soluble urokinase plasminogen activator receptor (suPAR) has been identified as a biomarker for incident chronic kidney disease (CKD). Proenkephalin (proENK) also has been shown to be a biomarker for renal dysfunc...

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Bibliographic Details
Main Authors: Jana C. Mossanen, Jessica Pracht, Tobias U. Jansen, Lukas Buendgens, Christian Stoppe, Andreas Goetzenich, Joachim Struck, Rüdiger Autschbach, Gernot Marx, Frank Tacke
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:International Journal of Molecular Sciences
Subjects:
acute kidney injury
soluble urokinase plasminogen activator receptor
suPAR
proenkephalin
pro-ENK
cardiac surgery
biomarker
acute kidney failure
Online Access:https://www.mdpi.com/1422-0067/18/8/1662

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https://www.mdpi.com/1422-0067/18/8/1662

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