A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

Abstract Background Pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in triple-negative breast cancer (TNBC) varies between 30 and 40% approximately. To provide further insight into the prediction of pCR, we evaluated the role of an epigenetic methylation-based signature. Me...

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Bibliographic Details
Main Authors: Begoña Pineda, Angel Diaz-Lagares, José Alejandro Pérez-Fidalgo, Octavio Burgués, Inés González-Barrallo, Ana B. Crujeiras, Juan Sandoval, Manel Esteller, Ana Lluch, Pilar Eroles
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Clinical Epigenetics
Subjects:
Triple-negative breast cancer
Prediction
Epigenetic signature
Online Access:http://link.springer.com/article/10.1186/s13148-019-0626-0

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http://link.springer.com/article/10.1186/s13148-019-0626-0

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