Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

During endoplasmic reticulum-associated degradation (ERAD), the cytoplasmic enzyme N-glycanase 1 (NGLY1) is proposed to remove N-glycans from misfolded N-glycoproteins after their retrotranslocation from the ER to the cytosol. We previously reported that NGLY1 regulates Drosophila BMP signaling in a...

Full description

Bibliographic Details
Main Authors: Antonio Galeone, Joshua M Adams, Shinya Matsuda, Maximiliano F Presa, Ashutosh Pandey, Seung Yeop Han, Yuriko Tachida, Hiroto Hirayama, Thomas Vaccari, Tadashi Suzuki, Cathleen M Lutz, Markus Affolter, Aamir Zuberi, Hamed Jafar-Nejad
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
ERAD
N-glycosylation
deglycosylation
BMP signaling
retrotranslocation
NGLY1
Online Access:https://elifesciences.org/articles/55596

Internet

https://elifesciences.org/articles/55596

Similar Items