Evaluation of the Cross-Protective Efficacy of a Chimeric Porcine Reproductive and Respiratory Syndrome Virus Constructed Based on Two Field Strains

Evaluation of the Cross-Protective Efficacy of a Chimeric Porcine Reproductive and Respiratory Syndrome Virus Constructed Based on Two Field Strains

One of the major hurdles to porcine reproductive and respiratory syndrome (PRRS) vaccinology is the limited or no cross-protection conferred by current vaccines. To overcome this challenge, a PRRS chimeric virus (CV) was constructed using an FL12-based cDNA infectious clone in which open reading fra...

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Bibliographic Details
Main Authors: Nadeem Shabir, Amina Khatun, Salik Nazki, Bumseok Kim, Eun-Jin Choi, Dong Sun, Kyoung-Jin Yoon, Won-Il Kim
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Viruses
Subjects:
porcine reproductive and respiratory syndrome
chimeric virus
cytokines
serum virus neutralizing antibodies
vaccine
pig
Online Access:http://www.mdpi.com/1999-4915/8/8/240

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http://www.mdpi.com/1999-4915/8/8/240

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