Oral administration of sodium butyrate reduces chemically-induced preneoplastic lesions in experimental carcinogenesis Administração oral de butirato de sódio reduz lesões pré-neoplásicas quimicamente induzidas na carcinogênese experimental

OBJECTIVE: The objective was to assess the effects of oral administration of sodium butyrate on colon carcinogenesis. METHODS: Carcinogenesis in adult male Wistar rats was induced with 1.2-dimethylhydrazine injections at a dose of 40mg/kg of body weight. A solution of sodium butyrate (3.4%) was give...

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Main Authors: Maria do Carmo Gouveia Peluzio, Ana Paula Boroni Moreira, Isabela Campelo de Queiroz, Cristina Maria Ganns Chaves Dias, Sylvia do Carmo Castro Franceschini, Jacqueline Isaura Alvarez-leite, Antônio José Natali, Céphora Maria Sabarense
Format: Article
Language:English
Published: Pontifícia Universidade Católica de Campinas 2009-10-01
Series:Revista de Nutrição
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732009000500012