Derivation and 97% Purification of Human Thyroid Cells From Dermal Fibroblasts

Derivation and 97% Purification of Human Thyroid Cells From Dermal Fibroblasts

Background: The success in rescuing thyroid deficiency in mice using thyroid cells derived from embryonic stem (ES) cells, together with the discovery of human induced pluripotent stem cells (iPSCs) from somatic cells, has raised the possibility of patient-specific thyroid cell replacement. In this...

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Bibliographic Details
Main Authors: Risheng Ma, Rui Shi, Syed A. Morshed, Rauf Latif, Terry F. Davies
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Endocrinology
Subjects:
induced pluripotent stem cells (iPSCs)
thyroid differentiation
PAX8
NKX2-1
TAZ
NIS
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00446/full

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https://www.frontiersin.org/article/10.3389/fendo.2020.00446/full

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