The Human SLC1A5 Neutral Amino Acid Transporter Catalyzes a pH-Dependent Glutamate/Glutamine Antiport, as Well

ASCT2 is a neutral amino acid transporter, which catalyzes a sodium-dependent obligatory antiport among glutamine and other neutral amino acids. The human ASCT2 over-expressed in Pichia pastoris and reconstituted in proteoliposomes has been employed for identifying alternative substrates of the tran...

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Bibliographic Details
Main Authors: Mariafrancesca Scalise, Tiziano Mazza, Gilda Pappacoda, Lorena Pochini, Jessica Cosco, Filomena Rovella, Cesare Indiveri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SLC
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00603/full