Lipid tethering of breast tumor cells reduces cell aggregation during mammosphere formation

Lipid tethering of breast tumor cells reduces cell aggregation during mammosphere formation

Abstract Mammosphere assays are widely used in vitro to identify prospective cancer-initiating stem cells that can propagate clonally to form spheres in free-floating conditions. However, the traditional mammosphere assay inevitably introduces cell aggregation that interferes with the measurement of...

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Bibliographic Details
Main Authors: Lekhana Bhandary, Patrick C. Bailey, Katarina T. Chang, Karen F. Underwood, Cornell J. Lee, Rebecca A. Whipple, Christopher M. Jewell, Eleanor Ory, Keyata N. Thompson, Julia A. Ju, Trevor M. Mathias, Stephen J. P. Pratt, Michele I. Vitolo, Stuart S. Martin
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81919-9

Internet

https://doi.org/10.1038/s41598-021-81919-9

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