TGFβ signaling curbs cell fusion and muscle regeneration

TGFβ signaling curbs cell fusion and muscle regeneration

The fusion of muscle progenitor cells to form syncytial myofibers is required for skeletal muscle development and regeneration. Here, the authors describe a novel and specific molecular regulation of muscle cell fusion driven by transforming growth factor beta (TGFβ) signaling.

Bibliographic Details
Main Authors: Francesco Girardi, Anissa Taleb, Majid Ebrahimi, Asiman Datye, Dilani G. Gamage, Cécile Peccate, Lorenzo Giordani, Douglas P. Millay, Penney M. Gilbert, Bruno Cadot, Fabien Le Grand
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20289-8

Internet

https://doi.org/10.1038/s41467-020-20289-8

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