Otoprotective Effect of 2,3,4′,5-Tetrahydroxystilbene-2-<i>O</i>-β-<span style="font-variant: small-caps">d</span>-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells

Otoprotective Effect of 2,3,4′,5-Tetrahydroxystilbene-2-<i>O</i>-β-<span style="font-variant: small-caps">d</span>-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells

Excessive levels of reactive oxygen species (ROS) lead to mitochondrial damage and apoptotic cell death in gentamicin-induced ototoxicity. 2,3,4’,5-Tetrahydroxystilbene-2-<i>O</i>-β-<span style="font-variant: small-caps;">d</span>-glucoside (THSG), a bioactive const...

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Bibliographic Details
Main Authors: Yu-Hsuan Wen, Jia-Ni Lin, Rong-Shuan Wu, Szu-Hui Yu, Chuan-Jen Hsu, Guo-Fang Tseng, Hung-Pin Wu
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
otoprotection
reactive oxygen species (ROS)
2,3,4′,5-tetrahydroxystilbene-2-<i>O</i>-β-<span style="font-variant: small-caps">d</span>-glucoside (THSG)
<i>Polygonum multiflorum</i> Thunb.
gentamicin
UB/OC-2 cells
Online Access:https://www.mdpi.com/1420-3049/25/13/3070

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https://www.mdpi.com/1420-3049/25/13/3070

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